Catalog Number: 5849
Chemical Name: 3-[2-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)ethynyl]benzoic acid
Biological Activity
Synthetic analogue of all trans-retinoic acid. Promotes differentiation of human embryonal carcinoma (EC) cells primarily into epithelial-like cells, along with a small number of neurons.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 50 mM in DMSO
  • Purity:
  • Storage:
    Store at +4°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Synthesis and evaluation of synthetic retinoid derivatives as inducers of stem cell differentiation.
    Christie et al.
    Org.Biomol.Chem., 2008;6:3497
  2. The action of all-trans-retinoic acid (ATRA) and synthetic retinoid analogues (EC19 and EC23) on human pluripotent stem cells differentiation investigated using single cell infrared microspectroscopy.
    Clemens et al.
    Mol.Biosyst., 2013;9:677
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