High affinity nicotinic agonist (Ki
values are 0.02 and 233 nM for α
2 and α
7 nicotinic receptors respectively). Analgesic.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Sold under license from the NIH, US Patent 5,314,899
Epibatidine, a potent analgesic and nicotinic agonist.
Badio and Daly
Comparative pharmacology of epibatidine; a potent agonist for neuronal nicotinic acetylcholine receptors.
Gerzarich et al.
Differential agonist inhibition identifies multiple epibatidine binidng sites in mouse brain.
Marks et al.
UB-165 implicates α4β2 nAChR in striatal dopamine release.
Sharples et al.
Epibatidine: a novel (chloropyridyl)azabicycloheptane with potent analgesic activity.
Spande et al.
The citations listed below are publications that use Tocris products. Selected citations for (±)-Epibatidine include:
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