Chemical Name: 6-Chloro-2,3,4,5-tetrahydro-1-(4-hydroxyphenyl)-1H-3-benzazepine-7,8-diol hydrochloride
Biological ActivityFenoldopam hydrochloride is a selective D1-like dopamine receptor partial agonist (EC50 = 57 nM). Vasodilator in vivo and does not readily cross the blood-brain barrier. Also α2-adrenoceptor antagonist in vitro (Ki = 15 - 25 nM).
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Tocris products are intended for laboratory research use only, unless stated otherwise.
Characterization of the peripheral and central effects of SK&F 82526, a novel DA receptor agonist.
Hahn et al.
Interactions of novel DArgic ligands with D-1 and D-2 DA receptors.
Sibley et al.
Life Sci., 1982;31:637
The pharmacology of fenol.
Nichols et al.
Citation for Fenoldopam hydrochloride
The citations listed below are publications that use Tocris products. Selected citations for Fenoldopam hydrochloride include:
1 Citation: Showing 1 - 1
Gastrin and D1 DA receptor interact to induce natriuresis and diuresis.
Authors: Chen Et al.
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