Flecainide acetate
Chemical Name: N-(2-Piperidylmethyl)-2,5-bis-(2,2,2-trifluoroethoxy)benzamide acetate
Purity: ≥99%
Biological Activity
Flecainide acetate is an open Na+ channel blocker that inhibits fast Na+ current in cardiac muscle in a use- and concentration-dependent manner. Orally-active class Ic antiarrhythmic agent.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Antiarrhythmics. 2. Synthesis and antiarrhythmic activity of N-(piperidylalkyl)trifluoroethoxybenzamides.
Banitt et al.
J.Med.Chem., 1977;20:821 -
The electrophysiology and pharmacology of verapamil, flecainide, and amiodarone: correlations with clinical effects and antiarrhythmic actions.
Singh et al.
Ann.N.Y.Acad.Sci., 1984;17:251 -
Use-and concentration-dependent effects of fleca. in guinea pig right ventricular muscle.
Rouet and Ducouret
J.Cardiovasc.Pharmacol., 1994;24:177
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Citation for Flecainide acetate
The citations listed below are publications that use Tocris products. Selected citations for Flecainide acetate include:
1 Citation: Showing 1 - 1
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Apamin does not inhibit human cardiac Na+ current, L-type Ca2+ current or other major K+ currents.
Authors: Yu Et al.
J Neurosci 2014;9:e96691
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