Flecainide acetate

Key Product Details

Product Description

Flecainide acetate is an open Na⁺ channel blocker that inhibits fast Na⁺ current in cardiac muscle in a use- and concentration-dependent manner. Orally-active class Ic antiarrhythmic agent.

Product Specifications for Flecainide acetate

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for Flecainide acetate

The following data is based on the product molecular weight 474.40.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

2 1 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.11 mL	10.54 mL	21.08 mL
5 mM	0.42 mL	2.11 mL	4.22 mL
10 mM	0.21 mL	1.05 mL	2.11 mL
50 mM	0.04 mL	0.21 mL	0.42 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 3 publications citing the usage of this product.

• Rouet and Ducouret Use-and concentration-dependent effects of fleca. in guinea pig right ventricular muscle. J.Cardiovasc.Pharmacol. 1994 PMID: 7526048
• Singh The electrophysiology and pharmacology of verapamil, flecainide, and amiodarone: correlations with clinical effects and antiarrhythmic actions. Ann.N.Y.Acad.Sci. 1984 PMID: 6395762
• Banitt Antiarrhythmics. 2. Synthesis and antiarrhythmic activity of N-(piperidylalkyl)trifluoroethoxybenzamides. J.Med.Chem. 1977 PMID: 874956

Product Documents for Flecainide acetate