Chemical Name: 2-Methyl-N-(4-nitro-3-[trifluoromethyl]phenyl)propanamide
Biological ActivityFlutamide is a non-steroidal antiandrogen; competitive antagonist of the androgen receptor. Blocks the biological activity of testosterone in vivo.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Flutamide. Mechanism of action of a new nonsteroidal antiandrogen.
Sufrin and Coffey
Induction of human arylamine N-acetyltransferase type I by androgens in human prostate cancer cells.
Butcher et al.
Cancer Res., 2007;67:85
Drug safety is a barrier to the discovery and development of new androgen receptor antagonists.
Foster et al.
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