Catalog Number: 4094
Alternate Names: SCH 13521
Chemical Name: 2-Methyl-N-(4-nitro-3-[trifluoromethyl]phenyl)propanamide
Biological Activity
Non-steroidal antiandrogen; competitive antagonist of the androgen receptor. Blocks the biological activity of testosterone (Cat. No. 2822) in vivo.
Technical Data
  • M.Wt:
    276.21
  • Formula:
    C11H11F3N2O3
  • Solubility:
    Soluble to 100 mM in DMSO and to 100 mM in ethanol
  • Purity:
    >99%
  • Storage:
    Store at RT
  • CAS No:
    13311-84-7
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Flutamide. Mechanism of action of a new nonsteroidal antiandrogen.
    Sufrin and Coffey
    Invest.Urol., 1976;13:429
  2. Induction of human arylamine N-acetyltransferase type I by androgens in human prostate cancer cells.
    Butcher et al.
    Cancer Res., 2007;67:85
  3. Drug safety is a barrier to the discovery and development of new androgen receptor antagonists.
    Foster et al.
    Prostate, 2011;71:480

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