Fumagillin

Catalog # Availability Size / Price Qty
1768/1
Fumagillin | CAS No. 23110-15-8 | Aminopeptidase Inhibitors
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Description: Methionine aminopeptidase-2 inhibitor; antiangiogenic

Chemical Name: (2E,4E,6E,8E)-Mono[(3R,4S,5S,6R)-5-methoxy-4-[(2R,3R)-2-methyl-3-(3-methyl-2-butenyl)oxiranyl]-1-oxaspiro[2.5]oct-6-yl] 2,4,6,8-decatetraenedioic acid ester

Product Details
Citations (1)
Reviews

Biological Activity

Antibiotic and antiangiogenic agent; covalently binds and inhibits methionine aminopeptidase-2. Inhibits endothelial cell proliferation in vitro and tumor-induced angiogenesis in vivo. Also inhibits tumor growth in mice.

Technical Data

M.Wt:
458.55
Formula:
C26H34O7
Solubility:
Soluble to 3 mM in ethanol
Storage:
Store at -20°C
CAS No:
23110-15-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citation for Fumagillin

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