Catalog Number: 1931
Alternate Names: GPAnt-2
Biological Activity
Substance P-related peptide that inhibits binding of G proteins to their receptors. Competitively and reversibly inhibits M2 muscarinic receptor activation of Gi or Go and inhibits Gs activation by β-adrenoceptors.
Technical Data
  • M.Wt:
  • Formula:
  • Sequence:

    (Modifications: X = Glp, Trp-3 = Trp-5 = Trp-6 = D-Trp, Met-7 = C-terminal amide)

  • Solubility:
    Soluble to 2 mg/ml in DMSO
  • Storage:
    Desiccate at -20°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. G protein antagonists. A novel hydrophobic peptide competes with receptor for G protein binding.
    Mukai et al.
    J.Biol.Chem., 1992;267:16237
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