Gatifloxacin

Tocris Bioscience | Catalog # 3849

Antibiotic; inhibits bacterial type II topoisomerase
Tocris Bioscience
Discontinued Product
3849 has been discontinued. View all Antibiotics products.

Key Product Details

Description

Antibiotic; inhibits bacterial type II topoisomerase

Alternative Names

AM 1155
View all Antibiotics »

Product Description

Fluoroquinolone antibiotic. Inhibits bacterial type II topoisomerases (IC50 values are 0.109 and 13.8 μg/ml for E.coli DNA gyrase and S.aureus topoisomerase IV respectively). Displays potent activity against gram-positive and gram-negative bacteria. Stimulates short-term self-renewal in both human and mouse embryonic stem cells in vitro.

Product Specifications for Gatifloxacin

Molecular Weight

375.39

Formula

C19H22FN3O4

Storage

Store at +4°C

Purity

≥98% (HPLC)

Chemical Name

1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid

CAS Number

112811-59-3

PubChem ID

5379

InChI Key

XUBOMFCQGDBHNK-UHFFFAOYSA-N

SMILES

O=C2C(C(O)=O)=CN(C3CC3)C1=C(OC)C(N4CC(C)NCC4)=C(F)C=C12

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 3.75 10 with gentle warming

Preparing Stock Solutions for Gatifloxacin

The following data is based on the product molecular weight 375.39.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.64 mL 133.19 mL 266.39 mL
0.5 mM 5.33 mL 26.64 mL 53.28 mL
1 mM 2.66 mL 13.32 mL 26.64 mL
5 mM 0.53 mL 2.66 mL 5.33 mL

Calculators

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Product Documents for Gatifloxacin

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Gatifloxacin

For research use only

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  • Gatifloxacin was used to understand its resistance pattern against S. aureus
    Name: Anonymous
    Species: Human
    Verified Customer | Posted 02/09/2019
    Gatifloxacin was used to understand its resistance pattern against S. aureus. E. coli strains were grown in Luria-Bertani medium, and S. aureus strains were grown in brain heart infusion medium for resistance study.
    Gatifloxacin 3849

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