Gatifloxacin

Catalog # Availability Size / Price Qty
3849/50
Antibiotics Small Molecule
1 Image
Description: Antibiotic; inhibits bacterial type II topoisomerase
Alternative Names: AM 1155

Chemical Name: 1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid

Purity: ≥98%

Product Details
Reviews (1)

Biological Activity

Fluoroquinolone antibiotic. Inhibits bacterial type II topoisomerases (IC50 values are 0.109 and 13.8 μg/ml for E.coli DNA gyrase and S.aureus topoisomerase IV respectively). Displays potent activity against gram-positive and gram-negative bacteria. Stimulates short-term self-renewal in both human and mouse embryonic stem cells in vitro.

Technical Data

M.Wt:
375.39
Formula:
C19H22FN3O4
Solubility:
Soluble to 10 mM in DMSO with gentle warming
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
112811-59-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Gatifloxacin was used to understand its resistance pattern against S. aureus
By Anonymous on 02/09/2019
Species: Human

Gatifloxacin was used to understand its resistance pattern against S. aureus. E. coli strains were grown in Luria-Bertani medium, and S. aureus strains were grown in brain heart infusion medium for resistance study.


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