GPBA receptor agonist. Upregulates GLP-1 secretion from intestinal cultures. Increases MQAE-fluorescence suggesting a decrease in intracellular chloride concentration in gallbladder epithelial cells.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Molecular mechanisms underlying bile acid-stimulated glucagon-like peptide-1 secretion.
Parker et al.
The membrane-bound bile acid receptor TGR5 is localized in the epithelium of human gallbladders.
Keitel et al.
The citations listed below are publications that use Tocris products. Selected citations for GPBAR-A include:
Showing Results 1 - 1 of 1