GPBAR-A

  ( 1 citations )    
Product Datasheet
Catalog Number:4478
Chemical Name:4-[[3,5-Bis(trifluoromethyl)phenyl]methyl]-6-(2-fluorophenyl)-4,5-dihydro-pyrido[3,2-f]-1,4-oxazepin-3(2H)-one
Product Details
Citations (1)
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Biological Activity
GPBA receptor agonist. Upregulates GLP-1 secretion from intestinal cultures. Increases MQAE-fluorescence suggesting a decrease in intracellular chloride concentration in gallbladder epithelial cells.
Technical Data
  • M.Wt:
    484.37
  • Formula:
    C23H15F7N2O2
  • Solubility:
    Soluble to 100 mM in DMSO and to 20 mM in ethanol
  • Purity:
    >98
  • Storage:
    Store at -20°C
  • CAS No:
    877052-79-4
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Product Datasheets
Citations:

The citations listed below are publications that use Tocris products. Selected citations for GPBAR-A include:

1 Citations: Showing 1 - 1

  1. Bile acid effects are mediated by ATP release and purinergic signalling in exocrine pancreatic cells.
    Authors: Kowal Et al.
    Stem Cells Transl Med  2015;13:28

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