Potent and selective 5-HT4
receptor antagonist (Ki
= 0.19 nM for porcine 5-HT4
). Centrally active following systemic administration in vivo
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Possible involvement of 5-HT4 receptors, in addition to 5-HT3 receptors, in the emesis induced by high-dose cisplatin in Suncus murinus.
Horikoshi et al.
Role of 5-HT4 receptors in the mouse passive avoidance test.
Galeotti et al.
Identification of serotonin 5-HT4 recognition sites in the porcine caudate nucleus by radioligand binding.
Schiavi et al.
The citations listed below are publications that use Tocris products. Selected citations for GR 125487 sulfamate include:
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