GR 79236
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Description: A1 agonist
Chemical Name: N-[(1S,2S)-2-Hydroxycyclopentyl]adenosine
Purity: ≥99%
Biological Activity
Adenosine A1 receptor agonist (Ki = 3.1 nM). Anticonvulsive in mice following systemic administration in vivo.Technical Data
M.Wt:
351.36
Formula:
C15H21N5O5
Solubility:
Soluble to 100 mM in water
Purity:
≥99%
Storage:
Desiccate at +4°C
CAS No:
124555-18-6
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Additional Information
Licensing Caveats:
Sold for research purposes under agreement from GlaxoSmithKline
Background References
-
Functional characterization of three adenosine receptor types.
Gurden et al.
Br.J.Pharmacol., 1993;109:693 -
Cardiovascular and antilipolytic effects of the adenosine agonist GR 79236.
Merkel et al.
Pharmacology, 1995;51:224 -
N-Substituted adenosines as novel neuroprotective A1 agonists with diminished hypotensive effects.
Knutsen et al.
J.Med.Chem., 1999;42:3463
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