GR 79236

Key Product Details

Product Description

Adenosine A₁ receptor agonist (K_i = 3.1 nM). Anticonvulsive in mice following systemic administration in vivo.

Licensing Information

Sold for research purposes under agreement from GlaxoSmithKline

Product Specifications for GR 79236

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for GR 79236

The following data is based on the product molecular weight 351.36.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

2 1 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.85 mL	14.23 mL	28.46 mL
5 mM	0.57 mL	2.85 mL	5.69 mL
10 mM	0.28 mL	1.42 mL	2.85 mL
50 mM	0.06 mL	0.28 mL	0.57 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Knutsen N-Substituted adenosines as novel neuroprotective A₁ agonists with diminished hypotensive effects. J.Med.Chem. 1999 PMID: 10479279
• Merkel Cardiovascular and antilipolytic effects of the adenosine agonist GR 79236. Pharmacology 1995 PMID: 8577816
• Gurden Functional characterization of three adenosine receptor types. Br.J.Pharmacol. 1993 PMID: 8358566

Product Documents for GR 79236