GW 627368

  ( 1 citations )    
Product Datasheet
Catalog Number:4668
Chemical Name:4-(4-,9-Diethoxy-1,3-dihydro-1-oxo-2H-benz[f]isoindol-2-yl)-N-(phenylsulfonyl)benzeneacetamide
Product Details
Citations (1)
Supplemental Products
Reviews
Biological Activity
Selective prostanoid EP4 receptor competitive antagonist with additional affinity at TP receptors (pKi values are 7.0 and 6.8 in competition radioligand bioassays). Affinity for all other prostanoid receptors is < 5.3. Inhibits U-46619 induced human platelet aggregation.
Technical Data
  • M.Wt:
    544.62
  • Formula:
    C30H28N2O6S
  • Solubility:
    Soluble to 100 mM in DMSO
  • Purity:
    >98
  • Storage:
    Store at -20°C
  • CAS No:
    439288-66-1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Licensing Caveats:
Sold for research purposes under agreement from GlaxoSmithKline.
Product Datasheets
Citations:

The citations listed below are publications that use Tocris products. Selected citations for GW 627368 include:

1 Citations: Showing 1 - 1

  1. Tissue factor/factor VIIa signalling promotes cytokine-induced beta cell death and impairs glucose-stimulated insulin secretion from human pancreatic islets.
    Authors: Ed&#233;n Et al.
    Diabetologia  2015;58:2563

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