Haloperidol hydrochloride

  ( 8 citations )    
Product Datasheet
Catalog Number:0931
Chemical Name:4-[4-(4-Chlorophenyl)-4-hydroxy-1-piperidinyl]-1-(4-fluorophenyl)-1-butanone hydrochloride
Product Details
Citations (8)
Supplemental Products
Reviews
Biological Activity
Dopamine antagonist with selectivity for D2-like receptors (Ki values are 1.2, ~ 7, 2.3, ~ 80 and ~ 100 nM for D2, D3, D4, D1 and D5 receptors respectively). Subtype-selective NMDA antagonist.
Technical Data
  • M.Wt:
    412.33
  • Formula:
    C21H23ClFNO2.HCl
  • Solubility:
    Soluble to 10 mM in ethanol with gentle warming and to 25 mM in DMSO with gentle warming
  • Purity:
    >99
  • Storage:
    Store at RT
  • CAS No:
    1511-16-6
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for Haloperidol hydrochloride include:

8 Citations: Showing 1 - 8
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  1. Theσ-1 receptors are present in monomeric and oligomeric forms in living cells in the presence and absence of ligands.
    Authors: Mishra Et al.
    Brain Res  2015;466:263
  2. Lateral diffusion of Gαs in the plasma membrane is decreased after chronic but not acute antidepressant treatment: role of lipid raft and non-raft membrane microdomains.
    Authors: Czysz Et al.
    J Biomol Screen  2015;40:766
  3. Curcumin Mitigates the Intracellular Lipid Deposit Induced by Antipsychotics In Vitro.
    Authors: Canfrán-Duque Et al.
    Biochem J  2015;10:e0141829
  4. Inhibition of tumor cell growth by Sigma1 ligand mediated translational repression.
    Authors: Kim Et al.
    Biochem Biophys Res Commun  2012;426:177
  5. HDAC2 regulates atypical antipsychotic responses through the modulation of mGlu2 promoter activity.
    Authors: Kurita Et al.
    Nat Neurosci  2012;15:1245
  6. The transport of nifurtimox, an anti-trypanosomal drug, in an in vitro model of the human blood-brain barrier: evidence for involvement of breast cancer resistance protein.
    Authors: Watson Et al.
    Neuropsychopharmacology  2012;1436:111
  7. Interaction between environmental and genetic factors modulates schizophrenic endophenotypes in the Snap-25 mouse mutant blind-drunk.
    Authors: Oliver and Davies
    Hum Mol Genet  2009;18:4576
  8. Differential regulation of central BDNF protein levels by antidepressant and non-antidepressant drug treatments.
    Authors: Balu Et al.
    Brain Res  2008;1211:37

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