Group I mGlu receptor antagonist (Ki
values are 140 and 110 μ
M at mGlu1a
receptors respectively). Decreases sEPSCs in rat pyramidal neurons in vitro
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Baseline glutamate levels affect group I and II mGluRs in layer V pyramidal neurons of rat sensorimotor cortex.
Bandrowski et al.
Synthesis and pharmacology of 3-isoxazolol amino acids as selective antagonists at group I metabotropic glutamic acid receptors.
Madsen et al.