HOE 140

Tocris Bioscience | Catalog # 3014

Potent and selective B2 antagonist
Tocris Bioscience

Key Product Details

Description

Potent and selective B2 antagonist

Alternative Names

Icatibant
View all Bradykinin Receptor Antagonists »

Product Description

HOE 140 is a potent and selective bradykinin B2 receptor antagonist (pA2 = 9.04). Also inhibits aminopeptidase N (Ki = 9.1 μM).

Product Specifications for HOE 140

Molecular Weight

1304.52

Formula

C59H89N19O13S

Storage

Store at -20°C

Purity

≥95% (HPLC)

CAS Number

130308-48-4

PubChem ID

90488794

InChI Key

QURWXBZNHXJZBE-JNFYKTHFSA-N

SMILES

[H]N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N1C[C@H](O)C[C@H]1C(=O)NCC(=O)N[C@H](CC1=CC=CS1)C(=O)N[C@@H](CO)C(=O)N1CC2=C(C[C@@H]1C(=O)N1C3CCCCC3C[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(O)=O)C=CC=C2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solubility Soluble to 1mg/ml in water

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 50 publications citing the usage of this product.

Product Documents for HOE 140

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for HOE 140

For research use only

Customer Reviews for HOE 140 (1)

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  • works good
    Name: Anonymous
    Species: Rat
    Assay Type: In Vitro
    Cell Line/Tissue: neurons
    Verified Customer | Posted 05/13/2020
    treat 20 min
    B2 receptor blocker HOE140, 200 nM
    HOE 140 3014

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