HOE 140

  ( 4 citations )    
Product Datasheet
Catalog Number:3014
Alternate Names:Icatibant
Chemical Name:
Product Details
Citations (4)
Supplemental Products
Reviews
Biological Activity
Potent and selective bradykinin B2 receptor antagonist (pA2 = 9.04). Also inhibits aminopeptidase N (Ki = 9.1 μM).
Technical Data
  • M.Wt:
    1304.52
  • Formula:
    C59H89N19O13S
  • Sequence:
    RRPXGXSXXR

    (Modifications: Arg-1 = D-Arg, X-4 = Hyp, X-6 = Thi, X-8 = D-Tic, X-9 = Oic)

  • Solubility:
    Soluble to 1 mg/ml in water
  • Storage:
    Store at -20°C
  • CAS No:
    130308-48-4
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Product Datasheets
COA view current batch
or select another batch:
Citations:

The citations listed below are publications that use Tocris products. Selected citations for HOE 140 include:

4 Citations: Showing 1 - 4
Filter your results:

  1. Modulation of cardiac vagal tone by bradykinin acting on nucleus ambiguus.
    Authors: Brailoiu
    Neuroscience  2017;365:23
  2. Angiotensin-(1-7) selectively induces relaxation and modulates endothelium-dependent dilation in mesenteric arteries of salt-fed rats
    Authors: Raffai Et al.
    Journal of Vascular Research  2016;53:105
  3. Functional expression of bradykinin B1 and B2 receptors in neonatal rat trigeminal ganglion neurons.
    Authors: Kawaguchi Et al.
    Oncogene  2015;9:229
  4. Nicotine exaggerates LPS-induced airway hyperreactivity via JNK-mediated up-regulation of Toll-like receptor 4.
    Authors: Xu Et al.
    Am J Respir Cell Mol Biol  2014;51:370

FAQs

No product specific FAQs exist for this product, however you may

View all Peptide FAQs

Have you used HOE 140?

Submit a review and receive a $25US/€18/£15/$25CAN amazon gift card if you include an image - $10US/€7/£6/$10CAN Amazon card for reviews without an image. Limited to verified customers in USA, Canada and Europe.

Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.

Order Details

Contact Us to Order
reload

Feedback

Customer Information
Calculators

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

R&D Systems Guarantee