Human SIRP beta 1/gamma Alexa Fluor® 350-conjugated Antibody

Catalog # Availability Size / Price Qty
FAB2096U-100UG
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Human SIRP beta 1/gamma Alexa Fluor® 350-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Detects human SIRP beta 1 and human SIRP gamma in direct ELISAs and Western blots.
Source
Monoclonal Mouse IgG2A Clone # 308906
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
Mouse myeloma cell line NS0-derived recombinant human SIRP beta 1
Gly26-Ala369 (Arg53His and Ala363Pro)
Accession # O00241.4
Formulation
Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.
Label
Alexa Fluor 350 (Excitation= 346 nm, Emission= 442 nm)

Applications

Recommended Concentration
Sample
Flow Cytometry
0.25-1 µg/106 cells
Human whole blood

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.

Background: SIRP beta 1/gamma

SIRP beta 1 is a type I transmembrane protein belonging to the SIRP family within the Ig superfamily. Members of this family are characterized by an extracellular region containing a V-set Ig domain containing a J-like sequence and two C1-set Ig domains. Unlike SIRP alpha that has cytoplasmic ITIM domains, SIRP beta 1 possesses positively charged residues that allow association with ITAM motif containing adaptor molecules. SIRP beta 1 is expressed on cells of monocyte, macrophage or dendritic lineages.

Long Name
Signal-regulatory Protein beta 1/gamma
Entrez Gene IDs
10326 (Human)
Alternate Names
SIRP beta 1/gamma

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