HX 630
Chemical Name: 4-(7,8,9,10-Tetrahydro-7,7,10,10-tetramethylbenzo[b]naphtho[2,3-f][1,4]thiazepin-12-yl-benzoic acid
Purity: ≥98%
Biological Activity
HX 630 is a RXR agonist. Acts as a retinoid synergist; enhances the potency of AM 80 (Cat. No. 3507) in a HL-60 cell differentiation assay.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Additional Information
Background References
-
Regulation of retinoidal actions by diazepinylbenzoic acids. Retinoid synergists which activate the RXR-RAR heterodimers.
Umemiya et al.
J.Med.Chem., 1997;40:4222 -
Effect of natural and synthetic retinoids on the proliferation and differentiation of three canine melanoma cell lines.
Ohashi et al.
J.Vet.Med.Sci., 2002;64:169 -
Clinically potential subclasses of retinoid synergists revealed by gene expression profiling.
Ishida et al.
Mol.Cancer Ther., 2003;2:49
Product Datasheets
Reconstitution Calculator
Molarity Calculator
FAQs
No product specific FAQs exist for this product, however you may
View all Small Molecule FAQsReviews for HX 630
There are currently no reviews for this product. Be the first to review HX 630 and earn rewards!
Have you used HX 630?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
