INSIG-1 Antibody Blocking Peptide

Name: INSIG-1 Antibody Blocking Peptide
Brand: Novus Biologicals
SKU: NB110-55244PEP
Price: 179 USD
Availability: InStock

Novus Biologicals | Catalog # NB110-55244PEP

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Product Specifications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Applications

Antibody Competition

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Product Specifications

Application Notes

This peptide is useful as a blocking peptide for NB110-55244. For further blocking peptide related protocol, click here.

Specificity

This peptide is specific for NB110-55244 only.

Protein / Peptide Type

Antibody Blocking Peptide

Formulation, Preparation, and Storage

NB110-55244PEP

Formulation	Peptide dissolved in dH20. Contains no BSA.
Preservative	No Preservative
Concentration	1 mg/ml
Shipping	The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at -80C. Avoid freeze-thaw cycles.

Background: INSIG-1

Insig1 is an insulin-induced gene. It encodes an endoplasmic reticulum (ER) membrane protein that plays a critical role in regulating cholesterol concentrations in cells.

Oxysterols regulate cholesterol homeostasis through liver X receptor (LXR) and sterol regulatory element-binding protein (SREBP) mediated signaling pathway. Insig1 binds to the sterol-sensing domains of SREBP cleavage-activating protein (SCAP) and HMG CoA reductase, and is essential for the sterol-mediated trafficking of the two proteins. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Alternate Names

CL6, CL-6, INSIG-1, INSIG-1 membrane protein, insulin induced gene 1, insulin-induced gene 1 protein, MGC1405

Gene Symbol

INSIG1

Additional INSIG-1 Products

Product Documents for INSIG-1 Antibody Blocking Peptide

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Certificate of Analysis

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Product Specific Notices for INSIG-1 Antibody Blocking Peptide

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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