IPSU

Catalog # Availability Size / Price Qty
5645/10
IPSU | CAS No. 1373765-19-5 | Orexin Receptor Antagonists
1 Image
Description: OX2 antagonist; orally bioavailable

Chemical Name: 2-(1H-Indol-3-ylmethyl)-9-(4-methoxy-2-pyrimidinyl)-2,9-diazaspiro[5.5]undecan-1-one

Purity: ≥98%

Product Details
Supplemental Products
Reviews

Biological Activity

OX2 receptor antagonist. Exhibits approximately six-fold selectivity for OX2 versus OX1 receptors. Decreases activity and increases sleep time in mice during the active phase, without affecting REM/NREM balance. Orally bioavailable. Brain penetrant.

Technical Data

M.Wt:
405.49
Formula:
C23H27N5O2
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in 1eq. HCl
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
1373765-19-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for IPSU

There are currently no reviews for this product. Be the first to review IPSU and earn rewards!

Have you used IPSU?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.