Biological Activity OX2 receptor antagonist. Exhibits approximately six-fold selectivity for OX2 versus OX1 receptors. Decreases activity and increases sleep time in mice during the active phase, without affecting REM/NREM balance. Orally bioavailable. Brain penetrant.
Soluble to 100 mM in DMSO and to 100 mM in 1eq. HCl
Store at +4°C
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