JTC 801

Catalog # Availability Size / Price Qty
2481/10
2481/50
JTC 801 | CAS No. 244218-51-7 | NOP Receptor Antagonists
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Description: Selective NOP antagonist

Chemical Name: N-(4-Amino-2-methyl-6-quinolinyl)-2-[(4-ethylphenoxy)methyl]benzamide hydrochloride

Purity: ≥98%

Product Details
Citations (3)
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Biological Activity

High affinity, selective NOP receptor antagonist (Ki = 8.2 nM). Displays approximately 12.5-, 129- and 1055-fold selectivity over human μ-, κ- and δ-opioid receptors respectively. Exhibits anti-nociceptive effects in acute pain models in vivo. Orally active.

Technical Data

M.Wt:
447.96
Formula:
C26H25N3O2.HCl
Solubility:
Soluble to 100 mM in DMSO and to 20 mM in ethanol
Purity:
≥98%
Storage:
Desiccate at RT
CAS No:
244218-51-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citations for JTC 801

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