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KCC 07

Catalog #: 6615 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
6615/10
6615/50
KCC 07 | CAS No. 315702-75-1 | p53 Activators
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Description: MBD2 (Methyl-CpG-binding domain protein 2) inhibitor

Chemical Name: 3-[[4-(2-Pyridinyl)-2-thiazolyl]amino]phenol

Purity: ≥98%

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Biological Activity

KCC 07 is a MBD2 (Methyl-CpG-binding domain protein 2) inhibitor. Prevents binding of MBD2 to methylated DNA and activates brain specific angiogenesis inhibitor 1 (BAI1)/p53 signaling. Inhibits medulloblastoma (MB) cell growth in vitro and reduces tumor size in mice bearing MB xenografts. Brain penetrant.

Technical Data

M.Wt:
269.32
Formula:
C14H11N3OS
Solubility:
Soluble to 100 mM in DMSO and to 20 mM in ethanol
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
315702-75-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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