KCC 07

Catalog # Availability Size / Price Qty
6615/10
6615/50
Cat.No. 6615 - KCC 07 | C14H11N3OS | CAS No. 315702-75-1
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Description: MBD2 (Methyl-CpG-binding domain protein 2) inhibitor

Chemical Name: 3-[[4-(2-Pyridinyl)-2-thiazolyl]amino]phenol

Purity: ≥98%

Product Details
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Biological Activity

MBD2 (Methyl-CpG-binding domain protein 2) inhibitor. Prevents binding of MBD2 to methylated DNA and activates brain specific angiogenesis inhibitor 1 (BAI1)/p53 signaling. Inhibits medulloblastoma (MB) cell growth in vitro and reduces tumor size in mice bearing MB xenografts. Brain penetrant.

Technical Data

M.Wt:
269.32
Formula:
C14H11N3OS
Solubility:
Soluble to 100 mM in DMSO and to 20 mM in ethanol
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
315702-75-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

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