p53 Activators: Products

p53 is well known for its key role as a tumor suppressor protein. It is 393 amino acids (aa) in length with a predicted molecular weight of 44 kDa. It belongs to the p53 family that also includes p63 and p73.

"p53 Activators" has 11 results in Products.
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Nutlin 3a 

MDM2 antagonist; active enantiomer of Nutlin-3 (Cat. No. 3984)

NSC 146109 hydrochloride 

Cell-permeable, genotype-selective antitumor agent; activates p53-dependent transcription

RITA 

MDM2-p53 interaction inhibitor

NSC 66811 

MDM2 antagonist. Disrupts MDM2-p53 interaction

WR 1065 dihydrochloride 

p53 activator. Also ROS scavenger

Tenovin-1 

Protects against MDM2-mediated p53 degradation

HLI 373 

Hdm2 inhibitor; activates p53-dependent transcription

SJ 172550 

MDMX inhibitor. Disrupts MDMX-p53 interaction

NSC 319726 

Reactivator of mutant p53

KCC 07 

MBD2 (Methyl-CpG-binding domain protein 2) inhibitor

Idasanutlin 

Potent MDM2 inhibitor; inhibits MDM2-p53 interaction
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