KHS 101 hydrochloride

Tocris Bioscience | Catalog # 4888

Selective inducer of neuronal differentiation in hippocampal neural progenitors
Tocris Bioscience
Discontinued Product
4888 has been discontinued. View all Compounds for Stem Cell Differentiation products.

Key Product Details

Description

Selective inducer of neuronal differentiation in hippocampal neural progenitors
View all Compounds for Stem Cell Differentiation »

Product Description

KHS 101 hydrochloride is a selective inducer of neuronal differentiation; induces neuronal differentiation in cultured hippocampal neural progenitor cells (NPCs) by interacting with TACC3 (EC50 ~1 μM). Suppresses astrocyte formation. Also induces acceleration of neuronal differentiation in the hippocampal dentate gyrus in vivo.

Product Specifications for KHS 101 hydrochloride

Molecular Weight

375.92

Formula

C18H21N5S.HCl

Storage

Desiccate at RT

Purity

≥98% (HPLC)

Chemical Name

N4-(2-Methylpropyl)-N2-[(2-phenyl-4-thiazolyl)methyl]-2,4-pyrimidinediamine hydrochloride

CAS Number

1784282-12-7

PubChem ID

90488983

InChI Key

INVQHPQJFRKGIO-UHFFFAOYSA-N

SMILES

CC(C)CNC1=NC(NCC2=CSC(C3=CC=CC=C3)=N2)=NC=C1.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 18.8 50
Ethanol 18.8 50

Preparing Stock Solutions for KHS 101 hydrochloride

The following data is based on the product molecular weight 375.92.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.5 mM 5.32 mL 26.60 mL 53.20 mL
2.5 mM 1.06 mL 5.32 mL 10.64 mL
5 mM 0.53 mL 2.66 mL 5.32 mL
25 mM 0.11 mL 0.53 mL 1.06 mL

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Background References

References are publications that support the biological activity of the product.

Product Documents for KHS 101 hydrochloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for KHS 101 hydrochloride

For research use only

Citations for KHS 101 hydrochloride

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