L-Azidonorleucine hydrochloride

Key Product Details

Product Description

L-Azidonorleucine hydrochloride is an unnatural amino acid; methionine surrogate. Can be incorporated into proteins by a mutant methionyl tRNA synthetase to enable cell-type specific analysis of protein synthesis. For use with bio-orthogonal non-canonical amino-acid tagging (BONCAT) or fluorescent non-canonical amino acid tagging (FUNCAT). Labeling does not affect the normal localization of the labeled proteins.

Product Specifications for L-Azidonorleucine hydrochloride

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for L-Azidonorleucine hydrochloride

The following data is based on the product molecular weight 208.65.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

4 3 2 1 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	4.79 mL	23.96 mL	47.93 mL
5 mM	0.96 mL	4.79 mL	9.59 mL
10 mM	0.48 mL	2.40 mL	4.79 mL
50 mM	0.10 mL	0.48 mL	0.96 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Mahdavi Engineered aminoacyl-tRNA synthetase for cell-selective analysis of mammalian protein synthesis. J.Am.Chem.Soc. 2016 PMID: 26991063
• Alvarez-Castelao Cell-type-specific metabolic labeling of nascent proteomes in vivo. Nat.Biotechnol. 2017 PMID: 29106408

Product Documents for L-Azidonorleucine hydrochloride