L-Azidonorleucine hydrochloride

Catalog # Availability Size / Price Qty
6585/10
Cat.No. 6585 - L-Azidonorleucine hydrochloride | C6H12N4O2.HCl | CAS No. 1454334-76-9
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Description: Unnatural amino acid for bio-orthogonal or fluorescent labeling of newly synthesized proteins

Chemical Name: (S)-2-Amino-6-azidohexanoic acid hydrochloride

Product Details
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Biological Activity

Unnatural amino acid; surrogate methionine. Can be incorporated into proteins by a mutant methionyl tRNA synthetase to enable cell-type specific analysis of protein synthesis. For use with bio-orthogonal non-canonical amino-acid tagging (BONCAT) or fluorescent non-canonical amino acid tagging (FUNCAT). Labeling does not affect the normal localization of the labeled proteins.

Technical Data

M.Wt:
208.65
Formula:
C6H12N4O2.HCl
Solubility:
Soluble to 100 mM in water
Storage:
Store at -20°C
CAS No:
1454334-76-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

Background References

  1. Cell-type-specific metabolic labeling of nascent proteomes in vivo.
    Alvarez-Castelao et al.
    Nat.Biotechnol., 2017;35:1196
  2. Engineered aminoacyl-tRNA synthetase for cell-selective analysis of mammalian protein synthesis.
    Mahdavi et al.
    J.Am.Chem.Soc., 2016;138:4278

Product Datasheets

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