LDN 27219

Biological Activity

Technical Data

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

1. Kinetic analysis of the interaction of tissue transglutaminase with a nonpeptidic slow-binding inhibitor.
   Case and Stein
   Biochemistry, 2007;46:1106
2. Discovery and structure-activity relationship of potent and selective covalent inhibitors of transglutaminase 2 for Huntington's disease.
   Prime et al.
   J.Med.Chem., 2012;55:1021
3. Structure-activity relationship study of novel tissue transglutaminase inhibitors.
   Duval et al.
   Bioorg.Med.Chem.Lett., 2005;15:1885
4. Histone serotonylation is a permissive modification that enhances TFIID binding to H3K4me3
   LA Farrelly, RE Thompson, S Zhao, AE Lepack, Y Lyu, NV Bhanu, B Zhang, YE Loh, A Ramakrishn, KC Vadodaria, KJ Heard, G Erikson, T Nakadai, RM Bastle, BJ Lukasak, H Zebroski, N Alenina, M Bader, O Berton, RG Roeder, H Molina, FH Gage, L Shen, BA Garcia, H Li, TW Muir, I Maze
   Nature, 2019;0(0):.

Product Datasheets