Active enantiomer of the prototypical Kir
) channel opener cromakalim
(Cat. No. 1377). Hypotensive and airways relaxant. IC50
= 490 nM in guinea pig trachea.
Soluble to 10 mM in DMSO
Store at RT
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
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Synthesis and smooth muscle relaxant activity of a new series of potassium channel activators: 3-amido-1,1-dimethylindan-2-ols.
Buckle et al.
Potassium channel modulation in rat portal vein by ATP depletion: a comparison with the effects of levcromakalim (BRL 38227).
Noack et al.
The inhibitory effects of cromakalim and its active enantiomer BRL 38227 against various agonists in guinea pig and human airways.
Taylor et al.
The citations listed below are publications that use Tocris products. Selected citations for Levcromakalim include:
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