Levcromakalim

Catalog # Availability Size / Price Qty
1378/10
1378/50
Levcromakalim | CAS No. 94535-50-9 | Inward Rectifier Potassium Channel Activators
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Description: Kir6 (KATP) channel opener; active enantiomer of Cromakalim
Alternative Names: BRL 38227

Chemical Name: (3S,4R)-3,4-dihydro-3-hydroxy-2,2-dimethyl-4-(2-oxo-1-pyrrolidinyl)-2H-1-benzopyran-6-carbonitrile

Purity: ≥99%

Product Details
Citations (3)
Reviews (1)

Biological Activity

Levcromakalim is an active enantiomer of the prototypical Kir6 (KATP) channel opener Cromakalim. Hypotensive and airways relaxant. IC50 = 490 nM in guinea pig trachea.

Technical Data

M.Wt:
286.33
Formula:
C16H18N2O3
Solubility:
Soluble to 10 mM in DMSO
Purity:
≥99%
Storage:
Store at RT
CAS No:
94535-50-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold under license

Product Datasheets

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Citations for Levcromakalim

The citations listed below are publications that use Tocris products. Selected citations for Levcromakalim include:

3 Citations: Showing 1 - 3

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Reviews for Levcromakalim

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Levcromakalim was used on BK channel opening properties compared to cromakalim
By Anonymous on 11/28/2018
Application: Species: Human

Levcromakalim was used on our lab to understand its BK channel opening properties compared to cromakalim. Results were reproducible.


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