Catalog Number: 1077
Chemical Name: 2-[(2R,6S)-6-[(2S)-2-Hydroxyphenethyl)]-1-methyl-2-piperidinyl]acetophenone hydrochloride
Biological Activity
High affinity, partial agonist with a Ki value of 4.4 nM in rat brain.
Technical Data
  • M.Wt:
    373.92
  • Formula:
    C22H27NO2.HCl
  • Solubility:
    Soluble to 50 mM in ethanol and to 10 mM in water
  • Storage:
    Store at RT
  • CAS No:
    134-63-4
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References

  1. Kishimoto T et al.
    Leucocyte Typing VI. Garland Publishing Inc. London.
  2. Pharmacology of lobeline, a nicotinic receptor ligand.
    Damaj et al.
    J.Pharmacol.Exp.Ther., 1997;282:410
  3. Lobeline, a nicotinic partial agonist attenuates alcohol consumption and preference in male C57BL/6J mice.
    Farook et al.
    Physiol.Behav., 2009;97:503

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