(-)-Lobeline hydrochloride

Tocris Bioscience | Catalog # 1077

Nicotinic partial agonist
Tocris Bioscience
Discontinued Product
1077 has been discontinued. View all Additional Nicotinic Receptor Agonists products.

Key Product Details

Description

Nicotinic partial agonist
View all Additional Nicotinic Receptor Agonists »

Product Description

(-)-Lobeline hydrochloride is a high affinity, partial agonist with a Ki value of 4.4 nM in rat brain.

Product Specifications for (-)-Lobeline hydrochloride

Molecular Weight

373.92

Formula

C22H27NO2.HCl

Storage

Store at RT

Chemical Name

2-[(2R,6S)-6-[(2S)-2-Hydroxyphenethyl)]-1-methyl-2-piperidinyl]acetophenone hydrochloride

CAS Number

134-63-4

PubChem ID

11527152

InChI Key

LPMXVESGRSUGHW-VGFRVVOQSA-N

SMILES

O[C@H]([C@]2=CC=CC=C2)C[C@@H]1CCC[C@H](CC(C3=CC=CC=C3)=O)N1C.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 10
Ethanol 50

Preparing Stock Solutions for (-)-Lobeline hydrochloride

The following data is based on the product molecular weight 373.92.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.5 mM 5.35 mL 26.74 mL 53.49 mL
2.5 mM 1.07 mL 5.35 mL 10.70 mL
5 mM 0.53 mL 2.67 mL 5.35 mL
25 mM 0.11 mL 0.53 mL 1.07 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for (-)-Lobeline hydrochloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for (-)-Lobeline hydrochloride

For research use only

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