High affinity protein disulfide isomerase (PDI) modulator (Kd
= 62 nM). Forces PDI to adopt an oxidized conformation and suppresses its activty. Neuroprotective.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Small molecule-induced oxidation of protein disulfide isomerase is neuroprotective.
Kaplan et al.