Breast cancer stem cell inhibitor (IC50
= 1.16 μ
M). Exhibits 24-fold selectivity for breast cancer stem cells over normal mammary epithelial cells. Also cytotoxic towards MDA-MB-231 breast cancer cells in vitro
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Identification of a selective small molecule inhibitor of breast cancer stem cells.
Germain et al.
Phenotypic high-throughput screening elucidates target pathway in breast cancer stem cell-like cells.
Carmody et al.