ML 3403

Catalog # Availability Size / Price Qty
4586/10
4586/50
ML 3403 | CAS No. 549505-65-9 | p38 Inhibitors
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Description: p38 inhibitor

Chemical Name: [5-[4-(4-Fluorophenyl)-2-methylthio-1H-imidazol-4-yl]-N-(1-phenylethyl)-2-pyridinamine

Purity: ≥98%

Product Details
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Biological Activity

p38 MAPK inhibitor (IC50 = 0.38 μM). Inhibits the release of IL-1β and TNF-α in a peripheral blood mononuclear cell (PBMC) assay (IC50 values are 0.039 and 0.16 μM respectively).

Technical Data

M.Wt:
404.5
Formula:
C23H21FN4S
Solubility:
Soluble to 100 mM in DMSO and to 50 mM in ethanol
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
549505-65-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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