ML 9 hydrochloride

  ( 4 citations )    
Product Datasheet
Catalog Number:0431
Chemical Name:1-(5-Chloronaphthalenesulfonyl)homopiperazine hydrochloride
Product Details
Citations (4)
Reviews
Biological Activity
Selective MLCK inhibitor (Ki values are 4, 32 and 54 μM for MLCK, PKA and PKC respectively). Also inhibits STIM1-plasma membrane interactions, preventing store-operated Ca2+ entry (SOCE).
Technical Data
  • M.Wt:
    361.29
  • Formula:
    C15H17ClN2O2S.HCl
  • Solubility:
    Soluble to 25 mM in DMSO
  • Purity:
    >99
  • Storage:
    Desiccate at RT
  • CAS No:
    105637-50-1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for ML 9 hydrochloride include:

4 Citations: Showing 1 - 4
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  1. Caffeine Modulates Vesicle Release and Recovery at Cerebellar Parallel Fibre Terminals, Independently of Calcium and Cyclic AMP Signalling.
    Authors: Dobson Et al.
    J Pharmacol Exp Ther  2015;10:e0125974
  2. Age-dependent contribution of Rho kinase in carbachol-induced contraction of human detrusor smooth muscle in vitro.
    Authors: Kirschstein Et al.
    Acta Pharmacol Sin  2014;35:74
  3. An essential role for inhibitor-2 regulation of protein phosphatase-1 in synaptic scaling.
    Authors: Siddoway Et al.
    PLoS One  2013;33:11206
  4. Differential roles for STIM1 and STIM2 in store-operated calcium entry in rat neurons.
    Authors: Gruszczynska-Biegala Et al.
    PLoS One  2011;6:e19285

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