Selective MLCK inhibitor (Ki
values are 4, 32 and 54 μ
M for MLCK, PKA and PKC respectively). Also inhibits STIM1-plasma membrane interactions, preventing store-operated Ca2+
Soluble to 25 mM in DMSO
Desiccate at RT
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
STIM and Orai: the long-awaited constituents of store-operated calcium entry.
Varnai et al.
Pharmacology of protein kinase inhibitors.
Hidaka and Koybashi
Effects of HA1077, a protein kinase inhibitor, on myosin phosphorylation and tension in smooth muscle.
Seto et al.
Pharmacology of the isoquinoline sulfonamide protein kinase C inhibitors.
Hidaka and Hagiwara
Trends Pharmacol.Sci., 1987;8:162
The citations listed below are publications that use Tocris products. Selected citations for ML 9 hydrochloride include:
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