Chemical Name: 2(E)-Butenedioic acid 1-methyl ester
Biological ActivityMMF is a nuclear factor (erythroid-derived-2)-like 2 (Nrf2) pathway activator. Also exhibits agonist activity at GPR109A. Primary metabolite of DMF (Cat. No. 4512).
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition
Antihepatotoxic activity of monomethyl fumarate isolated from Fumaria indica.
Rao & Mishra
Fumarates promote cytoprotection of central nervous system cells against oxidative stress via the nuclear factor (erythroid-derived 2)-like 2 pathway.
Scannevin et al.
Nicotinic acid- and monomethyl fumarate-induced flushing involves GPR109A expressed by keratinocytes and COX-2-dependent prostanoid formation in mice.
Hanson et al.
The psoriasis durg monomethylfumarate is a potent nicotinic receptor agonist.
Tang et al.
Citation for MMF
The citations listed below are publications that use Tocris products. Selected citations for MMF include:
1 Citation: Showing 1 - 1
Furin inhibitors block SARS-CoV-2 spike protein cleavage to suppress virus production and cytopathic effects.
Authors: Cheng Et al.
Cell Rep. 2020;
No product specific FAQs exist for this product, however you mayView all Small Molecule FAQs
Tocris Small Molecules
Reviews for MMF
There are currently no reviews for this product. Be the first to review MMF and earn rewards!
Have you used MMF?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image