MMK 1

Tocris Bioscience | Catalog # 3537

Potent and selective FPR2 agonist
Tocris Bioscience
Discontinued Product
3537 has been discontinued. View all Formyl Peptide Receptor Agonists products.

Key Product Details

Description

Potent and selective FPR2 agonist
View all Formyl Peptide Receptor Agonists »

Product Description

MMK 1 is a potent and selective human formyl peptide receptor FPR2 agonist (EC50 values are 1, 2 and > 10 000 nM at mFRP2, hFPR2 and hFPR1 respectively). Induces migration of human monocytes and neutrophils via a chemotactic mechanism and enhances production of proinflammatory cytokines IL-1β and IL-6. Also activates the neutrophil superoxide-generating NADPH-oxidase.

DMSO is not recommended as a solvent for this peptide.

Product Specifications for MMK 1

Molecular Weight

1610.97

Formula

C75H123N19O18S

Storage

Store at -20°C

Purity

≥95% (HPLC)

CAS Number

271246-66-3

PubChem ID

25074458

InChI Key

PWBQRCXCXXGUGY-AJOXZCOLSA-N

SMILES

[H]N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCSC)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solubility Soluble to 0.5mg/ml in 25% ethanol / water with sonication

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 14 publications citing the usage of this product.

Product Documents for MMK 1

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for MMK 1

For research use only

Customer Reviews for MMK 1 (1)

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  • Following protocol
    Name: Christopher Durrant
    Species: Human
    Assay Type: Ex Vivo
    Verified Customer | Posted 01/09/2020
    Followed publication
    looking at human formyl peptide receptor

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