MS 15203

Catalog # Availability Size / Price Qty
6299/5
6299/25
MS 15203 | CAS No. 73912-52-4 | GPR171 Agonists
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Description: Potent and selective GPR171 partial agonist

Chemical Name: 5-[(2-Methyl-1-oxo-2-propen-1-yl)amino]-1,3-benzenedicarboxylic acid

Purity: ≥98%

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Biological Activity

MS 15203 is a potent and selective GPR171 partial agonist (EC50 = 90 nM; 28% inhibition of Forskolin activated adenylyl cyclase activity in rat hypothalamic membranes). Exhibits minimal binding to a panel of ~70 GPCRs and 10 other receptors (<22% of radioligand displaced from the target receptors). Increases neuronal activity in the paraventricular nucleus. Increases food intake and body weight in mice.

Technical Data

M.Wt:
249.22
Formula:
C12H11NO5
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
73912-52-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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