Cell-permeable activator of adenylyl cyclase. Hypotensive and vasodilatory agent. Induces neuronal differentiation in stem cells and in several neuroblastoma. Used to reprogram mouse embryonic fibroblasts to induced pluripotent stem cells in combination with three other small molecules (Cat. Nos. 3742
). Also available as part of the PKA Tocriset™
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Other Product-Specific Information:
Interactions of forskolin and adenylate cyclase.
Awad et al.
Forskolin: a specific stimulator of adenylyl cyclase or a diterpene with multiple sites of action?
Laurenza et al.
Structure-activity relationships for activation of adenylate cyclase by the diterpene forskolin and its derivatives.
Seamon et al.
cAMP induces neuronal differentiation of mesenchymal stem cells via activation of extracellular signal-regulated kinase/MAPK.
Kim et al.
Pluripotent stem cells induced from mouse somatic cells by small-molecule compounds.
Hou et al.
The citations listed below are publications that use Tocris products. Selected citations for Forskolin include:
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