Key Product Details

Species Reactivity

Human

Applications

Blockade of Receptor-ligand Interaction

Label

PerCP (Excitation = 490 nm, Emission = 675 nm)

Antibody Source

Monoclonal Mouse IgG1 Clone # 99211
View all MSPR/Ron Primary Antibodies »

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant human MSP R
Met1-Ser956
Accession # Q04912

Specificity

Detects human MSP in direct ELISAs. In this format, this antibody shows less than 2% cross-reactivity with recombinant mouse (rm) MSP R. Recognizes an epitope found in the beta chain.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Applications for MSPR/Ron Antibody (99211) [PerCP]

Application
Recommended Usage

Blockade of Receptor-ligand Interaction

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from ascites

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: MSPR/Ron

Ron, the tyrosine kinase receptor for the Macrophage-stimulating protein, is involved in cell dissociation, motility, and matrix invasion (1). Ron, a cDNA homologous to the hepatocyte growth factor (HGF) receptor gene (MET), encodes a putative tyrosine kinase. It has been shown that the Ron gene is expressed in several epithelial tissues as well as in granulocytes and monocytes. The major RON transcript is translated into a glycosylated single chain precursor, cleaved into a 185 kDa heterodimer (p185Ron) of 35 (alpha) and 150 kDa (beta) disulfide-linked chains, before exposure at the cell surface (2).

Long Name

Macrophage Stimulating Protein Receptor

Alternate Names

CD136, MSP R, MST1R, Ron

Gene Symbol

MST1R

Additional MSPR/Ron Products

Product Documents for MSPR/Ron Antibody (99211) [PerCP]

Certificate of Analysis

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Product Specific Notices for MSPR/Ron Antibody (99211) [PerCP]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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FAQs

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