Catalog Number: 2655
Chemical Name: (2S)-2-(6-Methoxy-2-naphthyl)propanoic acid sodium salt
Biological Activity
Non-selective cyclooxygenase (COX) inhibitor that displays anti-inflammatory, antipyretic and analgesic effects. Has a neuroprotective role against colchicine-induced cognitive impairment and oxidative stress.
Technical Data
  • M.Wt:
    252.24
  • Formula:
    C14H13NaO3
  • Solubility:
    Soluble to 100 mM in water
  • Purity:
    >99%
  • Storage:
    Desiccate at RT
  • CAS No:
    26159-34-2
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Protective effect of naproxen (non-selective COX-inhibitor) or rofecoxib (selective COX-2 inhibitor) on immobilization stress-induced behavioral and biochemical alterations in mice.
    Dhir et al.
    Eur.J.Pharmacol., 2006;535:192
  2. Naproxen sodium.
    Sutton
    J.Am.Pharm.Assoc. (Wash), 1996;NS36:633
  3. Differential effects of cyclooxygenase inhibitors on intracerebroventricular colchicine-induced dysfunction and oxidative stress in rats.
    Kumar et al.
    Eur.J.Pharmacol., 2006;551:58

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