Catalog Number: 2924
Chemical Name: 6-S-[(4-Nitrophenyl)methyl]-6-thioinosine
Biological Activity
Equilibrative nucleoside transporter 1 (ENT1) inhibitor (Ki values are 0.4 and 2800 nM for hENT1 and hENT2 respectively).
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 100 mM in DMSO
  • Purity:
  • Storage:
    Desiccate at +4°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Kinetic and pharmacological properties of cloned human equilibrative nucleoside transporters, ENT1 and ENT2, stably expressed in nucleoside transporter-deficient PK15 cells.
    Ward et al.
    J.Biol.Chem., 2000;275:8375
  2. Human equilibrative nucleoside transporter 1, as a predictor of 5-fluorouracil resistance in human pancreatic cancer.
    Tsujie et al.
    Anticancer Res., 2007;27:2241
  3. Synthesis and flow cytometric evaluation, and identification of highly potent dipyridamole analogues as equilibrative nucleoside transporter 1 inhibitors.
    Lin and Buolamwini
    J.Med.Chem., 2007;50:3906

The citations listed below are publications that use Tocris products. Selected citations for NBMPR include:

Showing Results 1 - 2 of 2

  1. The NLRP3 inflammasome is activated by nanoparticles through ATP, ADP and adenosine.
    Authors: Baron Et al.
    J Exp Bot
  2. Chronic sleep restriction disrupts sleep homeostasis and behavioral sensitivity to alcohol by reducing the extracellular accumulation of adenosine.
    Authors: Clasadonte Et al.
    J Neurosci
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