Nilutamide

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Nilutamide | CAS No. 63612-50-0 | Androgen Receptor Antagonists
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Description: Androgen receptor antagonist. Orally active
Alternative Names: RU 23908

Chemical Name: 5,5-Dimethyl-3-[4-nitro-3-(trifluoromethyl)phenyl]-2,4-imidazolidinedione

Purity: ≥99%

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Biological Activity

Non-steroidal and silent antiandrogen. Binds to androgen receptors and also inhibits androgen biosynthesis in vitro. In rats in vivo it inhibits androgen-induced prostate weight increase and inhibits negative androgen-dependent gonadotropin feedback leading to an increase in luteinising hormone and testosterone. Orally active.

Technical Data

M.Wt:
317.22
Formula:
C12H10F3N3O4
Solubility:
Soluble to 25 mM in ethanol with gentle warming and to 25 mM in DMSO
Purity:
≥99%
Storage:
Store at RT
CAS No:
63612-50-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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