Chemical Name: N-(1,4-Dihydro-1,4-dioxo-2-naphthalenyl)-L-tryptophan
Biological Activity Potent inhibitor of Aβ oligomer and fibril formation (IC50 = 50 nM for formation of fibrils from Aβ1-42). Reduces cytotoxicity of Aβ oligomers and increases cell viability in neuronal cells. Significantly extends lifespan of Drosophila expressing human Aβ1-42.
Soluble to 100 mM in DMSO
Store at -20°C
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