11 results for "Amyloid beta Peptide Inhibitors" in Products

Amyloid beta Peptide Inhibitors

γ-secretase inhibitor; induces neuronal differentiation; blocks Notch signaling

Chemical Name: (2S)-N-[(3,5-Difluorophenyl)acetyl]-L-alanyl-2-phenyl]glycine 1,1-dimethylethyl ester
Purity: ≥99%
Using DAPT to differentiate hiPSCs into dopaminergic neurons
(2)
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Potent and selective γ-secretase inhibitor

Alternate Names: L 458,γ-Secretase Inhibitor X
Chemical Name: (5S)-(tert-Butoxycarbonylamino)-6-phenyl-(4R)-hydroxy-(2R)-benzylhexanoyl)-L-leucy-L-phenylalaninamide
Purity: ≥97%
Potent and selective γ-secretase inhibitor
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β-secretase (BACE) inhibitor; inhibits amyloid assembly

Alternate Names: Epigallocatechin gallate
Chemical Name: 3,4,5-Trihydroxybenzoic acid (2R,3R)-3,4-dihydro-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-2H-1-benzopyran-3-yl ester
Purity: ≥98%
β-secretase (BACE) inhibitor; inhibits amyloid assembly
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Inhibitor of Aβ42 fibril formation

Chemical Name: 2'-(4-Aminophenyl)-[2,5'-bi-1H-benzimidazol]-5-amine
Purity: ≥98%
Inhibitor of Aβ42 fibril formation
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Selective inhibitor of PKCβII

Chemical Name: 5,6-bis[(4-Fluorophenyl)amino]-1H-isoindole-1,3(2H)-dione
Purity: ≥98%
Selective inhibitor of PKCβII
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Potent γ-secretase inhibitor

Chemical Name: 2-[(1R)-1-[[(4-Chlorophenyl)sulfonyl](2,5-difluorophenyl)amino]ethyl-5-fluorobenzenebutanoic acid
Purity: ≥98%
Potent γ-secretase inhibitor
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PI 3-K/Akt/mTOR signaling inhibitor; blocks phosphorylation of Akt and p70S6K in vitro

Chemical Name: 3,8-Dihydroxy-6H-dibenzo[b,d]pyran-6-one
Purity: ≥98%
PI 3-K/Akt/mTOR signaling inhibitor; blocks phosphorylation of Akt and p70S6K in vitro
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Highly potent active component of ADNP; prevents amyloid β aggregation; active in vivo

Alternate Names: AL-108,NAP (peptide),NAPVSIPQ
Purity: ≥95%
Highly potent active component of ADNP; prevents amyloid β aggregation; active in vivo
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Potent γ-secretase inhibitor

Chemical Name: (2S)-2-[[(2S)-6,8-Difluoro-1,2,3,4-tetrahydro-2-naphthalenyl]amino]-N-[1-[2-[(2,2-dimethylpropyl)amino]-1,1-dimethylethyl]-1H-imidazol-4-yl]pentanamide dihydrobromide
Purity: ≥98%
Potent γ-secretase inhibitor
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γ-secretase inhibitor; attenuates amyloid plaque deposition

Chemical Name: N-[cis-4-[(4-Chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohexyl]-1,1,1-trifluoromethanesulfonamide
Purity: ≥98%
γ-secretase inhibitor; attenuates amyloid plaque deposition
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Inhibitor of JNK signaling

Chemical Name: (9S,10R,12R)-5-16-Bis[(ethylthio)methyl]-2,3,9,10,11,12-hexahydro-10-hydroxy-9-methyl-1-oxo-9,12-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid methyl ester
Purity: ≥97%
Inhibitor of JNK signaling
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