NS 5806

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NS 5806 | CAS No. 426834-69-7 | Voltage-gated Potassium Channel Activators
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Description: KV4.3 channel activator

Chemical Name: N-[3,5-Bis(trifluoromethyl)phenyl]-N'-[2,4-dibromo-6-(2H-tetrazol-5-yl)phenyl]urea

Purity: ≥99%

Product Details
Citations (1)

Biological Activity

NS 5806 is a KV4.3 channel activator; mediates the transient outward K+ current (Ito). Increases IKv4.3 peak current amplitude in CHO-K1 cells expressing KV4.3 and KChIP2 (EC50 = 5.3 μM). Inhibits KV1.4-mediated currents independently of KChIP2. Also slows the decay of KV4.2 and KV4.3 currents in the presence of KChIP2.

Technical Data

Soluble to 100 mM in DMSO and to 50 mM in ethanol
Store at +4°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citation for NS 5806

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