NS 5806

Catalog # Availability Size / Price Qty
4166/10
4166/50
Voltage-gated Potassium Channel Activators Small Molecule
1 Image
Description: KV4.3 channel activator

Chemical Name: N-[3,5-Bis(trifluoromethyl)phenyl]-N'-[2,4-dibromo-6-(2H-tetrazol-5-yl)phenyl]urea

Purity: ≥99%

Product Details
Citations (1)
Reviews (1)

Biological Activity

KV4.3 channel activator; mediates the transient outward K+ current (Ito). Increases IKv4.3 peak current amplitude in CHO-K1 cells expressing KV4.3 and KChIP2 (EC50 = 5.3 μM). Inhibits KV1.4-mediated currents independently of KChIP2. Also slows the decay of KV4.2 and KV4.3 currents in the presence of KChIP2.

Technical Data

M.Wt:
574.07
Formula:
C16H8Br2F6N6O
Solubility:
Soluble to 100 mM in DMSO and to 50 mM in ethanol
Purity:
≥99%
Storage:
Store at +4°C
CAS No:
426834-69-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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Citation for NS 5806

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Reviews for NS 5806

Average Rating: 4 (Based on 1 Review)

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NS 5806 shows channel opening properties and would use this product again
By Sadequl Islam on 10/12/2018
Species: Human

NS 5806 was studied to understand its channel opening properties. The product was dissolved in DMSO and it showed channel opening properties as expected. Performs well in experimental condition. Would recommend and use again.


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