NSC 146109 hydrochloride

Discontinued Product

2185 has been discontinued.
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NSC 146109 hydrochloride | CAS No. 59474-01-0 | p53 Activators
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Description: Cell-permeable, genotype-selective antitumor agent; activates p53-dependent transcription

Chemical Name: (10-Methyl-9-anthracenyl) methyl carbamimidothioic acid ester hydrochloride

Purity: ≥97%

Product Details
Citations (1)

Biological Activity

NSC 146109 hydrochloride is a cell-permeable, genotype-selective antitumor agent that activates p53-dependent transcription. Increases levels of endogenous p53 in tumor cells and protects p53 from Mdm2-mediated degradation. Displays some selectivity for tumor cells vs. normal cells in an MTT cell viability assay.

Technical Data

Soluble to 10 mM in ethanol and to 100 mM in DMSO
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citation for NSC 146109 hydrochloride

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