Chemical Name: (10-Methyl-9-anthracenyl) methyl carbamimidothioic acid ester hydrochloride
Biological Activity Cell-permeable, genotype-selective antitumor agent that activates p53-dependent transcription. Increases levels of endogenous p53 in tumor cells and protects p53 from Mdm2-mediated degradation. Displays some selectivity for tumor cells vs. normal cells in an MTT cell viability assay.
Soluble to 10 mM in ethanol and to 100 mM in DMSO
Desiccate at RT
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