NSC 146109 hydrochloride

Catalog # Availability Size / Price Qty
2185/10
2185/50
NSC 146109 hydrochloride | CAS No. 59474-01-0 | p53 Activators
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Description: Cell-permeable, genotype-selective antitumor agent; activates p53-dependent transcription

Chemical Name: (10-Methyl-9-anthracenyl) methyl carbamimidothioic acid ester hydrochloride

Purity: ≥99%

Product Details
Citations (1)
Reviews

Biological Activity

Cell-permeable, genotype-selective antitumor agent that activates p53-dependent transcription. Increases levels of endogenous p53 in tumor cells and protects p53 from Mdm2-mediated degradation. Displays some selectivity for tumor cells vs. normal cells in an MTT cell viability assay.

Technical Data

M.Wt:
316.85
Formula:
C17H16N2S.HCl
Solubility:
Soluble to 10 mM in ethanol and to 100 mM in DMSO
Purity:
≥99%
Storage:
Desiccate at RT
CAS No:
59474-01-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citation for NSC 146109 hydrochloride

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