NTNCB hydrochloride

Key Product Details

Product Description

NTNCB hydrochloride is a selective, non-peptide competitive NPY Y₅ antagonist. K_i values are 8.0 and 16032 nM at human recombinant Y₅ and Y₁ receptors respectively. Potently antagonizes NPY inhibition of forskolin-stimulated cAMP. Displays some affinity for cloned human D₂ and α_2C receptors (K_i values are 63 and 100 nM respectively).

Product Specifications for NTNCB hydrochloride

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for NTNCB hydrochloride

The following data is based on the product molecular weight 508.07.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

2 1 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.97 mL	9.84 mL	19.68 mL
5 mM	0.39 mL	1.97 mL	3.94 mL
10 mM	0.20 mL	0.98 mL	1.97 mL
50 mM	0.04 mL	0.20 mL	0.39 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Islam Discovery of potent and selective small molecule NPY Y5 receptor antagonists. Bioorg.Med.Chem.Lett. 2002 PMID: 12067557

Product Documents for NTNCB hydrochloride