Home / NPY Receptor Antagonists / NTNCB hydrochloride

NTNCB hydrochloride

2155 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
2155/10
2155/50
NTNCB hydrochloride | CAS No. 191931-56-3 | NPY Receptor Antagonists
1 Image
Description: Potent and selective non-peptidic NPY Y5 antagonist

Chemical Name: 2-Nitro-N-[[trans-4-[[[(1,2,3,4-tetrahydro-2-naphthalenyl)methyl]amino]methyl]cyclohexyl]methyl]benzenesulfonamide hydrochloride

Purity: ≥98%

Product Details
Supplemental Products
Reviews
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

Selective, non-peptide competitive NPY Y5 antagonist. Ki values are 8.0 and 16032 nM at human recombinant Y5 and Y1 receptors respectively. Potently antagonizes NPY inhibition of forskolin-stimulated cAMP. Displays some affinity for cloned human D2 and α2C receptors (Ki values are 63 and 100 nM respectively).

Technical Data

M.Wt:
508.07
Formula:
C25H33N3O4S.HCl
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at RT
CAS No:
191931-56-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Discovery of potent and selective small molecule NPY Y5 receptor antagonists.
    Islam et al.
    Bioorg.Med.Chem.Lett., 2002;12:1767

Product Datasheets

COA view current batch
Or select another batch:
SDS
Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

VersaClone cDNA Plasmids

Human NPY5R (NP_006165) VersaClone cDNA

RDC0159

Reviews for NTNCB hydrochloride

There are currently no reviews for this product. Be the first to review NTNCB hydrochloride and earn rewards!

Have you used NTNCB hydrochloride?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.