Selective, non-peptide competitive NPY Y5
values are 8.0 and 16032 nM at human recombinant Y5
receptors respectively. Potently antagonizes NPY inhibition of forskolin-stimulated cAMP. Displays some affinity for cloned human D2
values are 63 and 100 nM respectively).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Discovery of potent and selective small molecule NPY Y5 receptor antagonists.
Islam et al.