Chemical Name: 2-Pyridinyl[7-(4-pyridinyl)pyrazolo[1,5-a]pyrimidin-3-yl]methanone
Biological ActivityOcinaplon is a modulator of GABAA receptors. Displays modest selectivity for GABAA α1 receptors; displays partial agonist activity at α2-, α3- and α5-containing receptors. Exhibits anxiolytic activity.
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Tocris products are intended for laboratory research use only, unless stated otherwise.
Selective anxiolysis produced by ocinaplon, a GABAA receptor modulator.
Lippa et al.
GABAA receptors as targets for novel anxiolytic drugs.
Rupprecht et al.
World J.Biol.Psychiatry, 2006;7:231
Comparative cue generalization profiles of L-838,417, SL651498, zolpidem, CL218,872, ocinaplon, bretazenil, ZopiC., and various benzodiazepines in chlordiazep. and zol. drug discrimination.
Mirza et al.
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