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Subtype-selective GABAA modulator
GABA-mimetic; selectively interacts with β2- and β3-subunit containing GABAA receptors
Allosteric modulator of GABAA receptors
Potent positive allosteric modulator of GABAA receptors
Antagonist of neurosteroid potentiation and direct gating of GABAA
Positive allosteric modulator of GABAA receptors
Positive allosteric modulator of GABAA receptors; direct agonist at higher concentrations
KV7 channel activator; also GABAA modulator and indirect NMDA antagonist
Ligand of the translocator protein (TSPO); also GABAA receptor potentiator
GluK1 antagonist; inhibits carbonic anhydrase (CA) II and IV; also positive allosteric modulator of GABAA receptors
Postitive allosteric modulator of GABAA receptors
Positive allosteric modulator of GABAA receptors
Positive allosteric modulator of GABAA receptors; displays subunit selectivity
GABAA modulator; anxiolytic
α6β3γ2-selective GABAA positive allosteric modulator
Positive modulator of GABAA receptors; endogenous neurosteroid