receptor allosteric modulator (pEC50
= 8.24). Significantly increases binding of the CB1
H]CP 55.940 (pKb
= 5.67) and decreases binding of the CB1
inverse agonist [3
H]SR 141716A (pKb
= 5.95). Inhibits CB1
receptor antagonist efficacy in vitro
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Allosteric modulation of the Cannabinoid CB1 receptor.
Price et al.
Allosterism and the cannabinoid CB1 receptors: the shape of things to come.
Trends Pharmacol.Sci., 2007;28:567
The citations listed below are publications that use Tocris products. Selected citations for Org 27569 include:
Showing Results 1 - 1 of 1