OXF BD 02

Catalog # Availability Size / Price Qty
4928/10
4928/50
OXF BD 02 | CAS No. 1429129-68-9 | Bromodomain Inhibitors
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Description: Selective BRD4(1) inhibitor

Chemical Name: 3-(3,5-Dimethyl-4-isoxazolyl)-5-hydroxy-α-phenylbenzenemethanol

Purity: ≥98%

Product Details
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Biological Activity

OXF BD 02 is a selective inhibitor of the first bromodomain of BRD4 (BRD4(1)) (IC50 = 382 nM). Exhibits 2-3-fold selectivity for BRD4(1) over the CBP bromodomain and has little affinity for a range of other bromodomains. Reduces viability of lung adenocarcinoma cell lines and attenuates proliferation of MV-4-11 leukemia cells. Cell permeable.

Technical Data

M.Wt:
295.33
Formula:
C18H17NO3
Solubility:
Soluble to 100 mM in DMSO and to 10 mM in ethanol with gentle warming
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
1429129-68-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold with the agreement of the University of Oxford

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