PD 161570

  ( 2 citations )    
Product Datasheet
Catalog Number:3724
Chemical Name:N-[6-(2,6-Dichlorophenyl)-2-[[4-(diethylamino)butyl]amino]pyrido[2,3-d]pyrimidin-7-yl]-N'-(1,1-dimethylethyl)urea
Product Details
Citations (2)
Supplemental Products
Reviews
Biological Activity
Selective FGFR inhibitor (IC50 values are 40, 262 and 3700 nM for FGFR, PDGFR and EGFR respectively). Inhibits FGFR receptor phosphorylation (IC50 = 622 nM) and growth of A121 cells in vitro.
Technical Data
  • M.Wt:
    532.51
  • Formula:
    C26H35Cl2N7O
  • Solubility:
    Soluble to 100 mM in DMSO and to 100 mM in ethanol
  • Purity:
    >98
  • Storage:
    Store at -20°C
  • CAS No:
    192705-80-9
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Licensing Caveats:
Sold for research purposes under agreement from Pfizer Inc.
Product Datasheets
Citations:

The citations listed below are publications that use Tocris products. Selected citations for PD 161570 include:

2 Citations: Showing 1 - 2
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  1. Paracrine effects of embryo-derived FGF4 and BMP4 during pig trophoblast elongation.
    Authors: Magaña Et al.
    Dev Biol  2014;387:15
  2. Modulation of pluripotency in the porcine embryo and iPS cells.
    Authors: Rodríguez Et al.
    J Exp Bot  2012;7:e49079

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