Physostigmine analog that inhibits acetylcholinesterase. Inhibits production of amyloid precursor protein (APP) and Aβ
. Improves morris water maze performance of scopolamine-treated rats.
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All Tocris products are intended for laboratory research use only.
The cholinesterase inhibitor, phenserine, improves morris water maze performance of scopolamine-treated rats.
Janas et al.
Life Sci., 2005;76:1073
Identification of novel small molecule inhibitors of amyloid precursor protein synthesis as a route to lower Alzheimer's disease amyloid-β peptide.
Utsuki et al.
Expert Opin.Investig.Drugs, 2007;16:1087
The citations listed below are publications that use Tocris products. Selected citations for Phenserine include:
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