Catalog Number: 2967
Chemical Name: (3aS,8aR)-1,2,3,3a,8,8a-Hexahydro-1,3a,8-trimethylpyrrolo[2,3-b]indol-5-ol 5-(N-phenylcarbamate)
Biological Activity
Physostigmine analog that inhibits acetylcholinesterase. Inhibits production of amyloid precursor protein (APP) and Aβ. Improves morris water maze performance of scopolamine-treated rats.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 10 mM in DMSO and to 25 mM in ethanol
  • Purity:
  • Storage:
    Store at +4°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. The cholinesterase inhibitor, phenserine, improves morris water maze performance of scopolamine-treated rats.
    Janas et al.
    Life Sci., 2005;76:1073
  2. Identification of novel small molecule inhibitors of amyloid precursor protein synthesis as a route to lower Alzheimer's disease amyloid-β peptide.
    Utsuki et al.
    J.Pharmacol.Exp.Ther., 2006;318:855
  3. Phenserine.
    Expert Opin.Investig.Drugs, 2007;16:1087

The citations listed below are publications that use Tocris products. Selected citations for Phenserine include:

Showing Results 1 - 1 of 1

  1. Acetylcholine induces GABA release onto rod bipolar cells through heteromeric nicotinic receptors expressed in A17 amacrine cells.
    Authors: Elgueta Et al.
    Sci Rep
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