Phenserine

Key Product Details

Product Description

Physostigmine analog that inhibits acetylcholinesterase. Inhibits production of amyloid precursor protein (APP) and Aβ. Improves morris water maze performance of scopolamine-treated rats.

Product Specifications for Phenserine

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for Phenserine

The following data is based on the product molecular weight 337.42.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

3 2 1 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.25 mM	11.85 mL	59.27 mL	118.55 mL
1.25 mM	2.37 mL	11.85 mL	23.71 mL
2.5 mM	1.19 mL	5.93 mL	11.85 mL
12.5 mM	0.24 mL	1.19 mL	2.37 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 12 publications citing the usage of this product.

• Utsuki Identification of novel small molecule inhibitors of amyloid precursor protein synthesis as a route to lower Alzheimer's disease amyloid-β peptide. J.Pharmacol.Exp.Ther. 2006 PMID: 16690718
• Klein Phenserine. Expert Opin.Investig.Drugs 2007 PMID: 17594192
• Janas The cholinesterase inhibitor, phenserine, improves morris water maze performance of scopolamine-treated rats. Life Sci. 2005 PMID: 15620572

Product Documents for Phenserine